Osmotic pressure modulates single cell cycle dynamics inducing reversible growth arrest and reactivation of human metastatic cells

by Taïeb, Hubert M. & 6 more Authors | More information
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Authors Hubert M. Taïeb (1) , Daniela S. Garske (1), Jörg Contzen (2, 3, 4), Gossen Manfred (3, 4), Luca Bertinetti (5), Tom Robinson (6), Amaia Cipitria (1) Affiliations 1. Biomaterials/Extracellular Matrix in Disease and Regeneration, MPI of Colloids and Interfaces, 14476 Potsdam
2. Department of Experimental Neurology, Charité Universitätsmedizin Berlin, 10117 Berlin
3. Institute of Active Polymers, Helmholtz Zentrum Hereon, 14513 Teltow
4. Berlin Brandenburg Center for Regenerative Therapies, Charité Virchow Campus, 13353 Berlin
5. MPI of Colloids and Interfaces, 14476 Potsdam
6. Theory and Bio-Systems/Biomicrofluidic Systems, MPI of Colloids and Interfaces, 14476 Potsdam
Cite as Taïeb, Hubert M. et al. (2021). Osmotic pressure modulates single cell cycle dynamics inducing reversible growth arrest and reactivation of human metastatic cells. Max Planck Society. https://dx.doi.org/10.17617/3.64 Study Type(s) experimental
Keywords
cancer microenvironment, biophysical cues, osmotic pressure, dormancy, single cell cycle dynamics, fluorescent ubiquitination-based cell cycle indicator 2, FUCCI2, MPIKG, Migration, hypertonicity, Proliferation
Journal
Scientific Reports
Number of items in this collection 4 DOI https://dx.doi.org/10.17617/3.64 Creation date Wed Sep 09 16:51:54 CEST 2020 Last modification date Tue Jun 29 16:58:01 CEST 2021 Date of publication Tue Jun 29 16:57:56 CEST 2021 Permalink https://edmond.mpdl.mpg.de/imeji/collection/RAeQqxoAJ03WIEwS QR-code
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